Why Korean Aesthetic Clinics Trust Salmon PDRN for Skin Regeneration

In recent years, salmon PDRN (polydeoxyribonucleotide) has become one of the most sought-after ingredients in Korean aesthetic clinics—and for good reason. Originally used in medical skin repair treatments, PDRN has made its way into high-end skin boosters, injection therapies, and premium serums, thanks to its impressive ability to support skin regeneration and rejuvenation. 

What Is PDRN and Why Salmon? 

PDRN is a DNA-derived molecule sourced from salmon trout (Oncorhynchus mykiss) or chum salmon (Oncorhynchus keta). It consists of low molecular weight DNA fragments that interact with skin receptors, particularly the adenosine A2A receptor, to stimulate tissue repair, improve microcirculation, and promote collagen production (Kim et al., 2016, Ann Dermatol). 

In Korean clinics, salmon DNA is favored for its biocompatibility, meaning it integrates well with human skin without causing irritation, making it a safe and effective choice for a variety of treatments. 

How PDRN Is Used in Korean Clinics 

✔ Skin Boosters and Mesotherapy: PDRN is injected via micro-needling or mesotherapy to deeply hydrate, restore elasticity, and visibly improve skin texture. Patients typically notice smoother, brighter skin within a few sessions. 

✔ Post-Laser Recovery: After procedures like laser resurfacing or chemical peels, PDRN serums or masks are often applied to speed up healing, reduce redness, and support skin barrier repair. 

✔ Anti-Aging Treatments: PDRN is commonly used in combination with hyaluronic acid or peptides to reduce fine lines and plump sagging skin, providing a refreshed and youthful look without invasive surgery. 

✔ Daily Skincare Integration: High-performance PDRN serums are also recommended for at-home use between clinic visits to maintain skin health and prolong the results of professional treatments. 

The Results: Why Clients Love It 

📌 Improved hydration and plumpness 
📌 Enhanced skin elasticity and reduced fine lines 
📌 More radiant, even-toned complexion 
📌 Faster recovery after aesthetic procedures 

A 2016 clinical review (Kim et al.) highlighted PDRN’s ability to improve skin density and reduce photoaging, making it a gold standard ingredient in Korean aesthetic medicine. 

The Lemust Approach: Bringing Clinic-Level Care Home 

At Lemust, we’ve formulated our PDRN Glow Serum with premium salmon DNA, hyaluronic acid, peptides, and niacinamide—inspired by the best of K-beauty clinic protocols. Each drop delivers a concentrated dose of skin renewal benefits, so you can enjoy a healthier, smoother, more radiant complexion—even without clinic visits. 

Final Thoughts 

PDRN isn’t just a beauty trend—it’s a scientifically backed skin rejuvenation hero trusted by top Korean dermatologists and aesthetic clinics. With consistent use, you can experience the skin-smoothing, glow-enhancing benefits right at home.