Micro-Spicules and At-Home Microneedling: How They Compare to Clinical Treatments

At-home skincare has evolved far beyond basic creams. Today, advanced delivery systems like micro-spicules offer a way to achieve visible skin smoothing, glow, and improved absorption—without the intensity of professional microneedling or injectable treatments. But how do micro-spicules really compare to traditional microneedling or mesotherapy? Let’s break it down. 

What Are Micro-Spicules? 

Micro-spicules are microscopic, needle-like structures derived from marine sponges (usually Haliclona species). These tiny silica-based spines naturally form part of the sponge skeleton and, when purified and stabilized, are used in advanced skincare to: 

  • Provide gentle micro-exfoliation, 

  • Improve absorption of active ingredients, 

  • Stimulate skin renewal through micro-stimulation. 

When applied topically, spicules penetrate the outer layer of the skin, creating controlled micro-channels that boost skin turnover and enhance product absorption—all without actual needles. 

Depth Comparison: Spicules vs. Microneedling vs. Mesotherapy 

Treatment Type 

Penetration Depth 

Typical Use 

Micro-Spicules (Topical) 

~0.2 mm to 0.3 mm 

Gentle exfoliation, enhanced absorption, smoother texture at home 

At-Home Microneedling (Rollers, 0.25–0.5 mm) 

~0.25 mm to 0.5 mm 

Light collagen stimulation, improved glow, product penetration 

Clinical Microneedling (0.5–2.0 mm) 

0.5 mm to 2.0 mm 

Deeper collagen induction, acne scar treatment, fine lines 

Mesotherapy (Injectables) 

1.0 mm to 4.0 mm 

Injection of active solutions for hydration, brightening, or firming in clinical settings 

 

📌 Spicules target the upper epidermis, making them ideal for safe, regular use at home without risk of skin barrier damage or prolonged redness. 

📌 Professional microneedling and mesotherapy penetrate deeper layers (dermis), which can stimulate more intensive collagen production but require professional supervision and downtime. 

Benefits of Micro-Spicules for At-Home Use 

✔ Gentle yet effective micro-stimulation: Helps visibly refine texture and promotes smoother, more radiant skin. 
 ✔ Enhanced active delivery: Research shows spicules can increase transdermal absorption of actives by up to 490% (Zhou et al., 2014, J Control Release), improving the visible effects of ingredients like peptides, CICA, and hyaluronic acid. 
 ✔ Minimal irritation, no needles: A light tingling or prickle sensation fades within hours, with no prolonged redness or downtime. 
 ✔ Regular use for lasting benefits: Safe to use 2–3 times per week, making it ideal for ongoing skin maintenance between professional treatments.  

Why Spicule Serums Like Lemust Spicule Shot Are a Smart Choice 

Designed for daily use, our Spicule Shot Serum combines 100K micro-spicules with centella asiatica (CICA), peptides, and hyaluronic acid, delivering a multi-functional approach. 

Final Thoughts: Clinic-Inspired Results, At Home 

While professional treatments have their place, micro-spicule skincare offers a safe, effective way to refresh and rejuvenate skin at home. Whether you’re seeking brighter skin, smoother texture, or better absorption of active ingredients, spicules provide clinic-inspired results with everyday convenience. 

References 

  • Zhou L. et al. (2014). Microneedle-mediated transdermal delivery enhanced by sponge spicules. Journal of Controlled Release, 192: 10-18. 

  • Byun SY et al. (2018). Improvement of skin barrier function using marine sponge spicule therapy. Adv Dermatol Allergol, 35(5): 512–518. 

Back to blog